Clinical Outcomes between Amniotic Membrane Transplantation and Conjunctival Autograft Using Fibrin Glue for Pterygium Surgery

Purpose@#We compared clinical outcomes including recurrence rate between amniotic membrane transplantation (AMT) and conjunctival autograft using fibrin glue and minimal conjunctival sutures for pterygium surgery. @*Methods@#We retrospectively analyzed 217 eyes of 198 patients with pterygia who underwent surgery from May 2016 to December 2019. Pterygium excision was performed with conjunctival autograft or AMT, using fibrin glue with both. Recurrence rates and complications were evaluated between the two groups. @*Results@#Postoperative recurrences were noted in one of 185 eyes (0.5%) in the conjunctival autograft group, and in six of 32 eyes (18.8%) in the AMT group. The recurrence rate was significantly lower in the conjunctival autograft group (p < 0.001). Logistic regression analysis revealed that conjunctival autograft was associated with a significantly lower risk of pterygium recurrence compared to AMT (odds ratio, 0.023; 95% confidence interval, 0.003-0.206; p = 0.001). No ocular complication was noted in both groups during follow-up. @*Conclusions@#Pterygium excision with conjunctival autograft using fibrin glue was more effective in preventing recurrence compared to AMT.

Clinical Outcomes between Amniotic Membrane Transplantation and Conjunctival Autograft Using Fibrin Glue for Pterygium Surgery

Purpose@#We compared clinical outcomes including recurrence rate between amniotic membrane transplantation (AMT) and conjunctival autograft using fibrin glue and minimal conjunctival sutures for pterygium surgery. @*Methods@#We retrospectively analyzed 217 eyes of 198 patients with pterygia who underwent surgery from May 2016 to December 2019. Pterygium excision was performed with conjunctival autograft or AMT, using fibrin glue with both. Recurrence rates and complications were evaluated between the two groups. @*Results@#Postoperative recurrences were noted in one of 185 eyes (0.5%) in the conjunctival autograft group, and in six of 32 eyes (18.8%) in the AMT group. The recurrence rate was significantly lower in the conjunctival autograft group (p < 0.001). Logistic regression analysis revealed that conjunctival autograft was associated with a significantly lower risk of pterygium recurrence compared to AMT (odds ratio, 0.023; 95% confidence interval, 0.003-0.206; p = 0.001). No ocular complication was noted in both groups during follow-up. @*Conclusions@#Pterygium excision with conjunctival autograft using fibrin glue was more effective in preventing recurrence compared to AMT.

Analysis of Corneal Topographic Optical Zone and Decentration after Myopic Refractive Surgery

PURPOSE: To identify factors influencing the ablation center and to evaluate the size of the ablation zone after PRK and LASIK using Technolas 217 C. METHODS: This study examined the results of refractive surgery using Technolas 217 C Excimer laser with eye tracking system in 69 eyes, of which 31 underwent PRK and 38 LASIK. The ablation zone and degree of decentration were determined through corneal topography. We divided the eyes into two groups according to the degree of decentration: less than 0.5 mm as the first group, and from 0.5 to 1.0 mm as the second. The ablation zone diameter in topography was compared with the programmed preoperative optical zone. RESULTS: The only factor influencing the ablation center in the PRK group was preoperative spherical equivalent(p=0.016), and no factor influenced the ablation zone in the LASIK group. In both groups, the long axis of the ablation zone was longer than that of the programmed optical zone(p=0.003), while the short axis was shorter (p=0.001). CONCLUSIONS: After refractive surgery using Technolas 217 C Excimer laser with eye tracking system, there was no clinically significant decentration. With greater preoperative spherical equivalent, more decentered ablation was noted in the PRK group. The topographical long axis of the ablation zone was longer than that of the programmed ablation zone, while the short axis of the ablation zone was shorter. During refractive surgery, we should be aware of the possibility that the short axis of the postoperative ablation zone may be shorter than that of the programmed preoperative optical zone.

Three Cases of Waardenburg Syndrome Type 2 in a Korean Family

Waardenburg syndrome (WS) is a rare, autosomal dominant disorder characterized by sensorineural hearing loss, pigmentary disturbances of the skin, hair, and iris, and other developmental defects such as lateral displacement of both medial canthi and lacrimal puncta called dystopia canthorum. While mutations of the PAX3 (paired box) gene have been identified in about 99% of WS type 1 cases, WS type 2 is a heterogeneous group, with about 15% of cases caused by mutations in microphthalmia associated transcription factor (MITF). We have experienced three cases of typical WS type 2 in a Korean family, for whom full ocular examination and genetic studies were performed. The genetic studies revealed no mutation in either PAX3 or MITF genes. The genetic basis, as yet unknown for most cases of WS type 2, might be found with further investigation.

A Case of Eyelid Necrosis and Periorbital Necrotizing Fasciitis

PURPOSE: Necrotizing fasciitis is an uncommon soft tissue infection which spreads rapidly along subcutaneous fascial planes and produces overlying skin necrosis. We report a case of eyelid necrosis and periorbital necrotizing fasciitis. METHODS: A 64-year-old, previously healthy, male visited the emergency room complaining of acute facial edema. He had been using an ointment for itchy scalp lesion due to hair dye, and had multiple mosquito bites on his forehead. He took NSAIDs before the day of visit for headache. Physical examination showed erythematous swelling of soft tissue and tense fluctuant bullae on eyelid and periorbital area. On the 6th day of hospitalization bullae ruptured, and purplish discoloration and necrosis were noticed. RESULTS: Parenteral antibiotics and surgical debridement were applied. Wound cultures were positive for Staphylococcus aureus resistant to methicillin. Histology of the debrided tissue showed necrotizing inflammation. The full-thickness skin graft was performed over the exposed pretarsal and preseptal orbicularis muscle of the right eyelid. The skin defects were healed with the recovery of adequate eyelid function. CONCLUSIONS: We achieved satisfactory results with proper diagnosis and management such as parenteral antibiotics and surgical debridement in a case with eyelid and periorbital necrotizing fasciitis.

Noninvasive and Simple Correction of Prominent Ear

Prominent ear means congenital ear anomaly which has the obtuse conchoscapal angle caused by underdeveloped antihelix and has the larger concha shape than normal. It can be corrected by non-surgical method such as molding process with splint when ear cartilage keep flexibility right after birth and by surgical method with manipulating the ear cartilage directly. To correct prominent ear, we used simple and effective technique consisted of (1)anterior cartilage surface scoring and (2)two horizontal mattress suture without skin excision because we have the opinion that the most important deformity in prominent ear is lesser projection of antihelical fold. From March 1998 to February 2003 this method was applied to 12 patients. During the follow-up period no particular side effects were detected and we had an excellent aesthetic result.

Bilateral Rapid Distraction of Mandible

Bilateral mandibular hypoplasia is found in Treacher Collins syndrome, Pierre Robin sequence, and bilateral craniofacial microsomia. It causes many aesthetic and functional problems such as facial deformities with malocclusion and airway problems. We have corrected bilateral hypoplastic mandible with distraction osteogenesis, which is a highlighted method in mandibular lengthening. For last 3 years 8 months, We applied this method to four bilateral cases, where were Treacher Collins syndrome patients and bilateral craniofacial microsomia patient in rapid multidirectional fashion. A complete ostectomy was made at angle of the mandible and the mandible was fixed 5 days after lengthening was started serially 1mm every 12 hours. After consolidation period for one to three month, the device was removed. We have distracted the mandibles in vertical plane, left.18.8mm, right. 13.4mm, in horizontal plane, left 13.9mm, right 13.7mm on the average. We could achieve good aesthetic results, and their airway problems were improved without any complications.

Chest Wall Reconstruction with Muscle Flap

The chest wall plays a role to protect vital organs in the trunk such as heart and lung, and to facilitate a semi-rigid structure for breathing. When a defect occurs in a chest wall for such reasons as trauma, tumor, infection, inflammation, post-radiation necrosis, congenital anomaly, and so forth, not only anatomical, but also functional aspects should be considered in reconstruction process. It is, generally speaking, difficult to reconstruct a chest wall defect, since these patients tend to be old aged and have underlying disease with chronic and heavily contaminated wounds which had experienced irradiation or operation. In chest wall reconstruction, the authors utilized muscle flaps in trunk to secure a semi-rigid structure, because muscle flaps in trunk are easily accessible, and have reliable blood vessels. We have conducted 42 cases of chest wall reconstruction between Feb, 1996 and Jan, 2003. Except one case, we succeeded in gaining satisfactory results in functional and anatomical aspects. Based on these experiences, we would like to clarify the principles of chest wall reconstruction as below, helping to choose a proper method in the operations. The principles are appropriate debridement, skeletal reconstruction when indicated, coverage of soft tissue with muscle flap and removal of dead spaces.